Add to Basket
|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Mastermind-Like 3 (Drosophila) (MAML3) (C-Term) antibody
|Synonyms||GDN, MAM2, CAGH3, ERDA3, MAM-2, TNRC3|
Alternatives Western Blotting (WB), ELISA
|2 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This MAML3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 645~675 amino acids from the C-terminal region of human MAML3.|
|Description||Other names: Mastermind-like protein 3, Mam-3, KIAA1816, MAML3|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This MAML3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 645~675 amino acids from the C-terminal region of human MAML3.|
|Molecular Weight||121780 DA|
Background: MAML3 acts as a transcriptional coactivator for NOTCH proteins. The protein has been shown to amplify NOTCH-induced transcription of HES1.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100 Immunohistochemistry ~~ 1:50~100 Flow cytometric~~1:10~50|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cancer, Transcription Factors, Signaling, Cell Structure|
|Restrictions||For Research Use only|
Lin, Oyama, Nagase et al.: "Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling." in: The Journal of biological chemistry, Vol. 277, Issue 52, pp. 50612-20, 2002 (PubMed).
Tonon, Modi, Wu et al.: "t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway." in: Nature genetics, Vol. 33, Issue 2, pp. 208-13, 2003 (PubMed).