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NUAK Family, SNF1-Like Kinase, 2 (NUAK2) (N-Term) antibody

Antigen

NUAK Family, SNF1-Like Kinase, 2 (NUAK2)

Synonyms SNARK, FLJ90349, DKFZp434J037, DKFZp686F01113, Snark, MGC93817, 1200013b22rik
Binding Site
Alternatives

N-Term

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN391234
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name NUAK2
Gene ID 81788
UniProt Q9H093
Immunogen This NUAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74~104 amino acids from the N-terminal region of human NUAK2.
Isotype Ig
Description Other names: NUAK family SNF1-like kinase 2, SNF1/AMP kinase-related kinase, SNARK, NUAK2,
Characteristics Purified Rabbit Polyclonal Antibody (Pab)
Specificity This NUAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74~104 amino acids from the N-terminal region of human NUAK2.
Molecular Weight 69612 DA
Comments

Background: Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.

Application Details

Application Notes The suggested dilution is: ELISA~~1:1,000 Western blotting~~1:50~100
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Protein Modifications, Cancer, Cell Structure
Restrictions For Research Use only

Publications

Product Lefebvre, Bai, Shahmolky et al.: "Identification and characterization of a novel sucrose-non-fermenting protein kinase/AMP-activated protein kinase-related protein kinase, SNARK." in: The Biochemical journal, Vol. 355, Issue Pt 2, pp. 297-305, 2001 (PubMed).

Alternatives

Alternatives for antigen "NUAK Family, SNF1-Like Kinase, 2 (NUAK2)", type "Antibodies"
Hosts Rabbit (28)
Reactivities Human (27), Mouse (Murine) (23), Rat (Rattus) (22), Cow (Bovine) (19), Dog (Canine) (19), Cat (Feline) (1), Chicken (1)
Applications Immunofluorescence (IF) (19), ELISA (13), Western Blotting (WB) (13), Immunohistochemistry (IHC) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes N-Term (2), Center (1)