CSNK1A1 antibody (C-Term)

Catalog No. ABIN391597

This Rabbit Polyclonal antibody specifically detects CSNK1A1 in WB and IHC (p). It exhibits reactivity toward Human.It has been mentioned in 1 publication

Quick Overview for CSNK1A1 antibody (C-Term) (ABIN391597)

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSNK1A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB00886

Product Details anti-CSNK1A1 Antibody

Binding Specificity: AA 309-337, C-Term

Predicted Reactivity: C, X

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CSNK1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the C-terminal region of human CSNK1A1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-CSNK1A1 antibody (ABIN391597)

Rodriguez, Yang, Hasselblatt, Liu, Zhou, Rauh-Hain, Ng, Choi, Fong, Agar, Welch, Berkowitz, Ng: "Casein kinase I epsilon interacts with mitochondrial proteins for the growth and survival of human ovarian cancer cells." in: EMBO molecular medicine, Vol. 4, Issue 9, pp. 952-63, (2012) (PubMed).

Target Details for CSNK1A1

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Alternative Name: CK1a

Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CK1a can phosphorylate a large number of proteins. This cytoplasmic protein participates in Wnt signaling. It has been demonstrated to phosphorylate CTNNB1 on Ser-45 and to interact with the Axin complex.

Molecular Weight: 38915

Gene ID: 1452

NCBI Accession: NP_001020276, NP_001258670, NP_001258671, NP_001883

UniProt: P48729

Pathways: WNT Signaling, Hedgehog Signaling