|+1 404 474 4654|
|+1 888 205 9894 (TF)|
ADAM Metallopeptidase Domain 9 (ADAM9) (N-Term) antibody
|Synonyms||adam9-A, MDC9, ADAM-9, Adam9, zgc:101824, ADAM9, LOC100101585, MCMP, Mltng, KIAA0021, AU020942, mKIAA0021|
Alternatives Western Blotting (WB), Flow Cytometry (FACS), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This ADAM9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42~72 amino acids from the N-terminal region of human ADAM9.|
|Description||Other names: Cellular disintegrin-related protein, Meltrin-gamma, Myeloma cell metalloproteinase, Metalloprotease/disintegrin/cysteine-rich protein 9, A disintegrin and metalloproteinase domain 9, ADAM 9, ADAM9, KIAA0021, MCMP, MDC9, MLTNG|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This ADAM9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42~72 amino acids from the N-terminal region of human ADAM9.|
|Molecular Weight||90556 DA|
Background: ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100 Flow cytometric~~1:10~50|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cell Signaling, Cell Structure, Neurology|
|Restrictions||For Research Use only|
Weskamp, Krätzschmar, Reid et al.: "MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains." in: The Journal of cell biology, Vol. 132, Issue 4, pp. 717-26, 1996 (PubMed).
McKie, Edwards, Dallas et al.: "Expression of members of a novel membrane linked metalloproteinase family (ADAM) in human articular chondrocytes." in: Biochemical and biophysical research communications, Vol. 230, Issue 2, pp. 335-9, 1997 (PubMed).
Hotoda, Koike, Sasagawa et al.: "A secreted form of human ADAM9 has an alpha-secretase activity for APP." in: Biochemical and biophysical research communications, Vol. 293, Issue 2, pp. 800-5, 2002 (PubMed).
|Hosts||Rabbit (29), Mouse (2), Goat (1), Rat (1)|
|Reactivities||Human (31), Mouse (Murine) (22), Rat (Rattus) (20), Dog (Canine) (19), Cow (Bovine) (18), Horse (Equine) (18), Pig (Porcine) (18), Rabbit (1), Xenopus laevis (1), Zebrafish (1)|
|Applications||Immunofluorescence (IF) (15), Western Blotting (WB) (15), ELISA (7), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunoprecipitation (IP) (2), Flow Cytometry (FACS) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)|
|Conjugates||Biotin (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)|
|Epitopes||C-Term (3), AA 1-697 (1), Internal Region (1), N-Term (1)|