EPH Receptor A5 (EPHA5) antibody

Details for Product No. ABIN391894
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Antigen
Synonyms CEK7, EHK-1, EHK1, EK7, HEK7, TYRO4, AI854630, AW125296, Cek7, Ehk1, Els1, Hek7, Rek7, bsk, Els1., EPHA5
Reactivity
Human
(96), (37), (30), (18), (18), (17), (1), (1), (1), (1)
Host
Rabbit
(64), (31), (1), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(6), (5), (5), (5), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(80), (62), (25), (14), (12), (2), (1)
Pubmed 1 reference available
Quantity 400 μL
Options
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Catalog No. ABIN391894
291.50 $
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Immunogen This EphA5 antibody is generated from rabbits immunized with his fusion recombinant protein of human EPHA5.
Clone RB16721
Isotype Ig
Specificity This EphA5 antibody is generated from rabbits immunized with his fusion recombinant protein of human EPHA5.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name EphA5
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Synonyms: Ephrin type-A receptor 5, Tyrosine-protein kinase receptor EHK-1, Eph homology kinase-1, Receptor protein-tyrosine kinase HEK7
Molecular Weight 114784 DA
Gene ID 2044
UniProt P54756
Research Area Phospho-specific antibodies, Stem Cells, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-EPH Receptor A5 (EPHA5) antibody Western blot analysis of EphA5 (arrow) using rabbit polyclonal EphA5 Antibody (ABIN391894). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the EphA5 gene (Lane 2) (Origene Technologies).
Background publications Fox, Holst, Chute et al.: "cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases." in: Oncogene, Vol. 10, Issue 5, pp. 897-905, 1995 (PubMed).

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