UCK antibody (C-Term)

Catalog No. ABIN392731

This Rabbit Polyclonal antibody specifically detects UCK in WB and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for UCK antibody (C-Term) (ABIN392731)

Target: UCK (Uridine-Cytidine Kinase (UCK))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UCK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB3876

Product Details anti-UCK Antibody

Binding Specificity: AA 132-162, C-Term

Predicted Reactivity: B, Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-162 amino acids from the C-terminal region of human UCK.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for UCK

Target: UCK (Uridine-Cytidine Kinase (UCK))

Alternative Name: UCK

Background: UCK1 (Uridine-cytidine kinase 1) phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. This enzyme does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Of note, UCK1 is able to use either ATP or GTP as a phosphate donor. UCK1 also possesses the ability to phosphorylate a number of cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.

Molecular Weight: 22222

Gene ID: 51727

NCBI Accession: NP_001129612, NP_057392

UniProt: P30085

Pathways: Nucleotide Phosphorylation