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Adaptor-Related Protein Complex 3, delta 1 Subunit (AP3D1) (AA 686-698) antibody

Details for Product No. ABIN401171, Supplier: Login to see
Antigen
  • wu:fj51g01
  • si:ch211-129c21.6
  • ADTD
  • hBLVR
  • AA407035
  • Ap3d
  • Bolvr
  • mBLVR1
  • mh
  • mocha
  • BLVR
Epitope
AA 686-698
6
2
2
1
Reactivity
Chimpanzee, Chicken, Human
17
5
5
1
1
1
Host
Goat
8
6
3
Clonality
Polyclonal
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
15
11
4
3
3
2
1
1
Supplier
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Immunogen Synthetic peptide corresponding aa 686-698 of Human AP3D1
Isotype IgG
Specificity This antibody is directed against AP3D1.
Cross-Reactivity (Details) Species reactivity (expected):Chimpanzee, Chicken, Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name AP3 Complex Subunit delta-1 (AP3D1 Antibody Abstract)
Background AP3D1 (also known as Delta-adaptin 3, AP-3 complex delta subunit and Deltaadaptin) is a subunit of the AP3 adaptor-like complex, which is not associated with clathrin. The AP3D1 subunit is implicated in intracellular biogenesis and trafficking of pigment granules and possibly platelet dense granules and neurotransmitter vesicles.Synonyms: AP3D1, Adapter-related protein complex 3 subunit delta-1, PRO0039, delta Adaptin
Gene ID 8943
NCBI Accession NP_001070991
UniProt O14617
Pathways
Application Notes ELISA: 1/5,000 - 1/20,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.6 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Supplier Images
 image for anti-Adaptor-Related Protein Complex 3, delta 1 Subunit (AP3D1) (AA 686-698) antibody (ABIN401171) anti-Adaptor-Related Protein Complex 3, delta 1 Subunit (AP3D1) (AA 686-698) antibody
Background publications Yen, Yeh, Chen et al.: "Detection of KRAS oncogene in peripheral blood as a predictor of the response to cetuximab plus chemotherapy in patients with metastatic colorectal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 13, pp. 4508-13, 2009 (PubMed).

Ooi, Moreira, DellAngelica et al.: "Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet." in: The EMBO journal, Vol. 16, Issue 15, pp. 4508-18, 1997 (PubMed).

Simpson, Peden, Christopoulou et al.: "Characterization of the adaptor-related protein complex, AP-3." in: The Journal of cell biology, Vol. 137, Issue 4, pp. 835-45, 1997 (PubMed).