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Details for Product No. ABIN401309

Histone Deacetylase 1 (HDAC1) (AA 466-482) antibody

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Antigen
Synonyms
GON-10, HD1, RPD3, RPD3L1, CG7471, DHDAC1, DRpd3, DmHDAC1, Dmel\\CG7471, E(var)3-64BC, HDAC, HDAC-1, HDAC1, Hdac1, Rpd3/HDAC, Su(var)3-26, Su(var)326, Su(var)328, dHDAC-1, dHDAC1, dRPD3, dRpd3, dmHDA4 ... show more
Epitope
»Alternatives AA 466-482
Reactivity
»Alternatives Cow (Bovine), Chimpanzee, Chicken, Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN401309
Quantity 0.1 mg
Price
379.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Synthetic peptide corresponding to amino acids 466-482 of Human HDAC-1
Isotype IgG
Specificity This antibody is directed against HDAC-1 protein.
Purification Affinity chromatography
Alternative Name HDAC1
Background HDAC1 (also known as HD1, histone deacetylase 1, RPD3, RPD3L1) belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Alternate names: HD1, Histone deacetylase 1, RPD3L1
Gene ID 3065
NCBI Accession NP_004955.2
UniProt Q13547
Research Area Cardiovascular, Hypertrophy, Wnt, DNA/RNA, Transcription Factors
Application Notes Western Blot: 1/1,000 - 1/5,000. ELISA: 1/10,000 - 1/50,000. Immunohistochemistry: 1/200 - 1/1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.33 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01% (w/v) Sodium Azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Expiry Date 12 months
Background publications Unoki, Nishidate, Nakamura: "ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain." in: Oncogene, Vol. 23, Issue 46, pp. 7601-10, 2004 (PubMed).

Alternatives for antigen "Histone Deacetylase 1 (HDAC1)", type "Antibodies"
Hosts (202), (48), (5)
Reactivities (243), (144), (136), (42), (39), (35), (16), (14), (5), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applications (196), (112), (73), (65), (46), (36), (33), (23), (9), (4), (3), (3), (2), (2), (1), (1)
Conjugates (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (1), (1)
Epitopes (45), (32), (26), (15), (8), (8), (8), (7), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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