SLIT3 antibody (AA 1164-1177)

Catalog No. ABIN401312

The Rabbit Polyclonal anti-SLIT3 antibody is suitable to detect SLIT3 in samples from Rat, Mouse, Human, Cow, Dog, Chicken and Chimpanzee. It has been validated for WB and EIA.

Quick Overview for SLIT3 antibody (AA 1164-1177) (ABIN401312)

Target: SLIT3 (Slit Homolog 3 (SLIT3))

Reactivity: Rat, Mouse, Human, Cow, Dog, Chicken, Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLIT3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SLIT3 Antibody

Binding Specificity: AA 1164-1177

Specificity: This antibody is directed against SLIT-3 protein.

Cross-Reactivity (Details): Species reactivity (expected):Rat, Canine, Bovine, Mouse, Chimpanzee, Chicken.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Synthetic peptide corresponding aa 1164-1177 of Human SLIT-3 protein

Isotype: IgG

Application Details

Application Notes: ELISA: 1/2,000 - 1/10,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.83 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for SLIT3

Target: SLIT3 (Slit Homolog 3 (SLIT3))

Alternative Name: SLIT3

Background: SLIT-3 (also known as multiple epidermal growth factorlike domain 5 and Slit homolog 3 protein) is a Slit protein. The 'slit' gene has been shown to play a critical role in central nervous system midline formation. In addition to SLIT3 there are two additional human 'slit' homologs, which are termed SLIT1 and SLIT2. Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. SLIT proteins may also participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions. Slit-3 is a secreted protein predominantly expressed in thyroid. Multiple isoforms have been reported for this product.Synonyms: KIAA0814, MEGF5, Multiple epidermal growth factor-like domains protein 5, SLIL2, SLIT-3, Slit homolog 3 protein

Gene ID: 6586

NCBI Accession: NP_003053

UniProt: O75094

Pathways: Regulation of Cell Size