ODF2 antibody (C-Term)

Catalog No. ABIN401414

The Rabbit Polyclonal anti-ODF2 antibody is suitable to detect ODF2 in samples from Human, Chimpanzee and Monkey. It has been validated for WB and EIA.

Quick Overview for ODF2 antibody (C-Term) (ABIN401414)

Target: ODF2 (Outer Dense Fiber of Sperm Tails 2 (ODF2))

Reactivity: Human, Chimpanzee, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ODF2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ODF2 Antibody

Binding Specificity: C-Term

Specificity: This antibody is specific for Cenexin-1 protein.

Cross-Reactivity (Details): Species reactivity (expected):Chimpanzee, Macaque.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Synthetic peptide corresponding to residues near the carboxy terminus

Isotype: IgG

Application Details

Application Notes: ELISA: 1/2,000 - 1/10,000. Western Blot: 1/200 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.1 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for ODF2

Target: ODF2 (Outer Dense Fiber of Sperm Tails 2 (ODF2))

Alternative Name: ODF2

Background: Cenexin-1, also known as ODF2 and outer dense fiber of sperm tails 2, are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. Cenexin-1 is one of the major outer dense fiber proteins. Multiple protein isoforms are encoded by transcript variants of the cenexin gene, however, not all isoforms and variants have been fully described.Synonyms: Cenexin, Outer dense fiber of sperm tails protein 2, Outer dense fiber protein 2

Gene ID: 4957

NCBI Accession: NP_002531

UniProt: Q5BJF6

Pathways: M Phase