LIM Domain Binding 2 Protein antibody (Middle Region)

Catalog No. ABIN404792

The Rabbit Polyclonal anti-LIM Domain Binding 2 Protein antibody is suitable to detect LIM Domain Binding 2 Protein in samples from Human, Mouse, Rat, Dog, Horse, Rabbit, Cow and Guinea Pig. It has been validated for WB.

Quick Overview for LIM Domain Binding 2 Protein antibody (Middle Region) (ABIN404792)

Target: LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIM Domain Binding 2 Protein antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LIM Domain Binding 2 Protein Antibody

Binding Specificity: Middle Region

Purpose: LDB2 Antibody - middle region

Sequence: LENTQYDAAN GMDDEEDFNN SPALGNNSPW NSKPPATQET KSENPPPQAS

Predicted Reactivity: Cow: 100%, Dog: 83%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against LDB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LDB2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104428

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for LIM Domain Binding 2 Protein

Target: LIM Domain Binding 2 Protein (LDB2) (LIM Domain Binding 2 (LDB2))

Alternative Name: LDB2

Background:

Background Information: LDB2 belongs to the LDB family. LDB2 binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. LIM domains are required for both inhibitory effects on LIM homeodomain transcription factors and synergistic transcriptional activation events. The inhibitory actions of the LIM domain can often be overcome by the LIM co-regulators known as CLIM2, LDB2 and NLI. LIM homeoproteins and CLIMs are involved in a variety of developmental processes.

Gene Name: LIM domain binding 2

Alternative Symbols: LDB1, CLIM1, LDB-2

Protein Name: LIM domain-binding protein 2

Molecular Weight: 43kDa

Gene ID: 9079

NCBI Accession: NP_001281

UniProt: O43679

Pathways: Stem Cell Maintenance