TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp) (N-Term) antibody

Details for Product No. ABIN404897, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms TIPARP, fc03g05, sb:cb841, si:dkey-33k14.4, wu:fc03g05, zgc:153056, ddf1, parp7, parp-1, parp-7, ARTD14, PARP7, pART14, AW558171, RM1
Epitope
N-Term
(7), (4), (3), (2), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(12), (5), (1)
Host
Rabbit
(15)
Clonality
Polyclonal
Application
Western Blotting (WB)
(13), (4), (2), (1), (1)
Pubmed 2 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 50 μg
Options
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the N terminal of human TIPARP
Blocking Peptide Blocking peptide for this product available: TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp) (N-Term) peptide (ABIN985108)
Sequence LKTCFKKKDQ KRLGTGTLRS LRPILNTLLE SGSLDGVFRS RNQSTDENSL
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Rabbit : 90 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against TIPARP. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TIPARP (Tiparp Antibody Abstract)
Background TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor, repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
Molecular Weight 76 kDa
Gene ID 25976
NCBI Accession NP_056323, NM_015508
UniProt Q7Z3E1
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 657 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp) (N-Term) antibody (ABIN404897) anti-TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp) (N-Term) antibody
Product cited in: MacPherson, Tamblyn, Rajendra et al.: "2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation." in: Nucleic acids research, Vol. 41, Issue 3, pp. 1604-21, 2013 (PubMed).

Mehrle, Rosenfelder, Schupp et al.: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, 2005 (PubMed).

Catalog No. ABIN404897
$289.00
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)