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TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp) (N-Term) antibody

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Synonyms TIPARP, fc03g05, sb:cb841, si:dkey-33k14.4, wu:fc03g05, zgc:153056, ddf1, parp7, parp-1, parp-7, ARTD14, PARP7, pART14, AW558171, RM1
(7), (4), (3), (2), (1)
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(12), (5), (1)
Western Blotting (WB)
(13), (4), (2), (1), (1)
Pubmed 2 references available
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Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the N terminal of human TIPARP
Blocking Peptide Blocking peptide for this product available: ABIN985108
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Rabbit : 90 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against TIPARP. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TIPARP (Tiparp Antibody Abstract)
Background TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor, repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
Molecular Weight 76 kDa
Gene ID 25976
NCBI Accession NP_056323, NM_015508
UniProt Q7Z3E1
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 657 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp) (N-Term) antibody (ABIN404897) anti-TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp) (N-Term) antibody
Product cited in: MacPherson, Tamblyn, Rajendra et al.: "2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation." in: Nucleic acids research, Vol. 41, Issue 3, pp. 1604-21, 2013 (PubMed).

Mehrle, Rosenfelder, Schupp et al.: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, 2005 (PubMed).

Catalog No. ABIN404897
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