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Tiparp antibody (N-Term)

Tiparp Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN404897
  • Target See all Tiparp Antibodies
    Tiparp (TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp))
    Binding Specificity
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 22
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
    Host
    • 24
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Tiparp antibody is un-conjugated
    Application
    • 12
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LKTCFKKKDQ KRLGTGTLRS LRPILNTLLE SGSLDGVFRS RNQSTDENSL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 83%, Pig: 100%, Rabbit: 92%, Rat: 83%
    Characteristics
    This is a rabbit polyclonal antibody against TIPARP. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human TIPARP
    Top Product
    Discover our top product Tiparp Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 657 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • MacPherson, Tamblyn, Rajendra, Bralha, McPherson, Matthews: "2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation." in: Nucleic acids research, Vol. 41, Issue 3, pp. 1604-21, (2013) (PubMed).

    Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

  • Target
    Tiparp (TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp))
    Alternative Name
    TIPARP (Tiparp Products)
    Synonyms
    TIPARP antibody, fc03g05 antibody, sb:cb841 antibody, si:dkey-33k14.4 antibody, wu:fc03g05 antibody, zgc:153056 antibody, ddf1 antibody, parp7 antibody, parp-1 antibody, parp-7 antibody, ARTD14 antibody, PARP7 antibody, pART14 antibody, AW558171 antibody, RM1 antibody, TCDD inducible poly(ADP-ribose) polymerase antibody, TCDD-inducible poly(ADP-ribose) polymerase antibody, TCDD-inducible poly [ADP-ribose] polymerase antibody, TIPARP antibody, tiparp antibody, LOC100018933 antibody, Tiparp antibody
    Background
    TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor, repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
    Alias Symbols: DDF1, DKFZP434J214, DKFZp686N0351, DKFZp686P1838, FLJ40466, PARP-1, PARP-7, PARP7, pART14
    Protein Interaction Partner: UBC, XRN2, ATM,
    Protein Size: 657
    Molecular Weight
    76 kDa
    Gene ID
    25976
    NCBI Accession
    NM_015508, NP_056323
    UniProt
    Q7Z3E1
    Pathways
    Platelet-derived growth Factor Receptor Signaling
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