ZFAND5 antibody (Middle Region)

Catalog No. ABIN404940

This anti-ZFAND5 antibody is a Rabbit Polyclonal antibody detecting ZFAND5 in WB. Suitable for Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow and Sheep. This Primary Antibody has been cited in 1 publication.

Quick Overview for ZFAND5 antibody (Middle Region) (ABIN404940)

Target: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFAND5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZFAND5 Antibody

Binding Specificity: Middle Region

Sequence: REDKITTPKT EVSEPVVTQP SPSVSQPSTS QSEEKAPELP KPKKNRCFMC

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against ZFAND5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ZFAND5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 213 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ZFAND5 antibody (ABIN404940)

He, Sun, Ou, Ding: "The protein Zfand5 binds and stabilizes mRNAs with AU-rich elements in their 3'-untranslated regions." in: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 24967-77, (2012) (PubMed).

Target Details for ZFAND5

Target: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Alternative Name: ZFAND5

Background: ZNF216 (ZFAND5) is a potent inhibitory factor for osteoclast differentiation and the mechanism is unlikely due to direct attenuation of the NF-kappa B pathway. It also has redundant and distinct roles in regulating apoptosis.
Alias Symbols: ZA20D2, ZFAND5A, ZNF216
Protein Interaction Partner: UBC, SRP19, APP, WIPF2, UBLCP1, ATP6V1H, TOMM34, SQSTM1, PSMD6, RAD23B, ZFAND5, RIPK1, TRAF6, IKBKG, TNFAIP3,
Protein Size: 213

Molecular Weight: 20 kDa

Gene ID: 7763

NCBI Accession: NM_006007, NP_005998

UniProt: O76080

Pathways: Platelet-derived growth Factor Receptor Signaling