Annexin IV antibody (Middle Region)

Catalog No. ABIN405097

This Rabbit Polyclonal antibody specifically detects Annexin IV in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Pig, Cow, Rabbit, Guinea Pig and Horse.

Quick Overview for Annexin IV antibody (Middle Region) (ABIN405097)

Target: Annexin IV (ANXA4) (Annexin A4 (ANXA4))

Reactivity: Human, Rat, Mouse, Dog, Pig, Cow, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin IV antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Annexin IV Antibody

Binding Specificity: Middle Region

Sequence: EGCLIEILAS RTPEEIRRIS QTYQQQYGRS LEDDIRSDTS FMFQRVLVSL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ANXA4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ANXA4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 321 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Annexin IV

Target: Annexin IV (ANXA4) (Annexin A4 (ANXA4))

Alternative Name: ANXA4

Background: Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 gene has 45 to 59 % identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59 % identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ANX4, DKFZp686H02120, MGC75105, PIG28, ZAP36
Protein Interaction Partner: PADI4, UBC, EZH2, DNAJB11, MPST, ANXA7, ANXA3, ANXA1, TINF2, POT1, SUMO2, NMT2, SMPD1, Cdk1, UCHL5, H2AFX, NFKB1, GP2,
Protein Size: 321

Molecular Weight: 36 kDa

Gene ID: 307

NCBI Accession: NM_001153, NP_001144

UniProt: P09525