Ecto-NOX Disulfide-Thiol Exchanger 1 (ENOX1) (Middle Region) antibody

Details for Product No. ABIN405361
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Antigen
Synonyms CNOX, PIG38, bA64J21.1, cCNOX, B230207J08, D230005D02Rik, RGD1306118
Epitope
Middle Region
(2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Xenopus laevis, Human, Chicken
(5), (1), (1)
Host
Rabbit
(3), (2)
Clonality
Polyclonal
Application
Western Blotting (WB)
(5), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN405361
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human ENOX1
Sequence QQLQFLQQTM QGMQQQLLTI QEELNNKKSE LEQAKEEQSH TQALLKVLQE
Predicted Reactivity Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, African clawed frog : 90 %
Characteristics This is a rabbit polyclonal antibody against ENOX1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ENOX1
Background Electron transport pathways are generally associated with mitochondrial membranes, but non-mitochondrial pathways are also biologically significant. Plasma membrane electron transport pathways are involved in functions as diverse as cellular defense, intracellular redox homeostasis, and control of cell growth and survival. Members of the ecto-NOX family, such as CNOX, or ENOX1, are involved in plasma membrane transport pathways. These enzymes exhibit both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity in series, with each activity cycling every 22 to 26 minutes.Electron transport pathways are generally associated with mitochondrial membranes, but non-mitochondrial pathways are also biologically significant. Plasma membrane electron transport pathways are involved in functions as diverse as cellular defense, intracellular redox homeostasis, and control of cell growth and survival. Members of the ecto-NOX family, such as CNOX, or ENOX1, are involved in plasma membrane transport pathways. These enzymes exhibit both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity in series, with each activity cycling every 22 to 26 minutes (Scarlett et al., 2005 [PubMed 15882838]).
Molecular Weight 73 kDa
Gene ID 55068
NCBI Accession NM_017993, NP_060463
UniProt Q8TC92
Research Area Cancer
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 643 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Ecto-NOX Disulfide-Thiol Exchanger 1 (ENOX1) (Middle Region) antibody WB Suggested Anti-ENOX1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysate
Background publications Oh, Yang, Hahn et al.: "Transcriptome analysis of human gastric cancer." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 16, Issue 12, pp. 942-54, 2005 (PubMed).

Validation Images
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