ENOX1 antibody (Middle Region)

Catalog No. ABIN2779123

This Rabbit Polyclonal antibody specifically detects ENOX1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Saccharomyces cerevisiae.

Quick Overview for ENOX1 antibody (Middle Region) (ABIN2779123)

Target: ENOX1 (Ecto-NOX Disulfide-Thiol Exchanger 1 (ENOX1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENOX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ENOX1 Antibody

Binding Specificity: Middle Region

Purpose: ENOX1 Antibody - middle region

Sequence: QQLQFLQQTM QGMQQQLLTI QEELNNKKSE LEQAKEEQSH TQALLKVLQE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against ENOX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ENOX1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40886-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ENOX1

Target: ENOX1 (Ecto-NOX Disulfide-Thiol Exchanger 1 (ENOX1))

Alternative Name: ENOX1

Background:

Background Information: Electron transport pathways are generally associated with mitochondrial membranes, but non-mitochondrial pathways are also biologically significant. Plasma membrane electron transport pathways are involved in functions as diverse as cellular defense, intracellular redox homeostasis, and control of cell growth and survival. Members of the ecto-NOX family, such as CNOX, or ENOX1, are involved in plasma membrane transport pathways. These enzymes exhibit both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity in series, with each activity cycling every 22 to 26 minutes.Electron transport pathways are generally associated with mitochondrial membranes, but non-mitochondrial pathways are also biologically significant. Plasma membrane electron transport pathways are involved in functions as diverse as cellular defense, intracellular redox homeostasis, and control of cell growth and survival. Members of the ecto-NOX family, such as CNOX, or ENOX1, are involved in plasma membrane transport pathways. These enzymes exhibit both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity in series, with each activity cycling every 22 to 26 minutes (Scarlett et al., 2005 [PubMed 15882838]).[supplied by OMIM].

Gene Name: Ecto-NOX disulfide-thiol exchanger 1

Alternative Symbols: CNOX, PIG38, cCNOX, bA64J21.1

Protein Name: Ecto-NOX disulfide-thiol exchanger 1

Molecular Weight: 73kDa

Gene ID: 55068

NCBI Accession: NP_060463

UniProt: Q8TC92