Hydroxyacid Oxidase 2 (HAO2) (N-Term) antibody

Catalog No. ABIN405407

The Rabbit Polyclonal anti-Hydroxyacid Oxidase 2 antibody is suitable to detect Hydroxyacid Oxidase 2 in samples from Human, Mouse, Rat, Horse, Dog, Pig, Cow and Rabbit. It has been validated for WB.

Quick Overview for Hydroxyacid Oxidase 2 (HAO2) (N-Term) antibody (ABIN405407)

Target: Hydroxyacid Oxidase 2 (HAO2)

Reactivity: Human, Mouse, Rat, Horse, Dog, Pig, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Purpose: HAO2 Antibody - N-terminal region

Sequence: DDNIAAFKRI RLRPRYLRDV SEVDTRTTIQ GEEISAPICI APTGFHCLVW

Predicted Reactivity: Cow: 85%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HAO2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HAO2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41434-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Hydroxyacid Oxidase 2 (HAO2)

Alternative Name: HAO2

Background:

Background Information: HAO2 is one of three related proteins that have 2-hydroxyacid oxidase activity yet differ in amino acid sequence, tissue expression and substrate preference. Subcellular location of the protein is the peroxisome. Specifically, the protein is expressed predominantly in liver and kidney and has the highest activity toward the substrate 2-hydroxypalmitate. Two alternatively spliced variants encoding the same isoform have been described.This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed predominantly in liver and kidney and has the highest activity toward the substrate 2-hydroxypalmitate. Two alternatively spliced variants encoding the same isoform have been described.

Gene Name: Hydroxyacid oxidase 2 (long chain)

Alternative Symbols: GIG16, HAOX2

Protein Name: Hydroxyacid oxidase 2

Molecular Weight: 39kDa

Gene ID: 51179

NCBI Accession: NP_001005783

UniProt: Q9NYQ3

Pathways: Monocarboxylic Acid Catabolic Process