Podoplanin (PDPN) antibody
| Antigen |
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| Synonyms |
T1A, GP36, GP40, Gp38, OTS8, T1A-2, AGGRUS, HT1A-1, PA2.26, T1a, OTS-8, T1alpha, RANDAM-2, E11, RTI40, T1-alpha, PDPN |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Conjugate
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Alexa Fluor (8), PE (7), Biotin (4), FITC (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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Western Blotting (WB) (55), Flow Cytometry (FACS) (32), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (30), Immunofluorescence (IF) (24), Immunoprecipitation (IP) (19), ELISA (18), Immunohistochemistry (IHC) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (14), Immunocytochemistry (ICC) (6), Immunohistochemistry (Fixed) (IHC (fx)) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Fluorescence Microscopy (FM) (1), Immunoelectron Microscopy (IEM) (1), Intracellular Staining (IS) (1)
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| Catalog no. |
ABIN405667 |
| Quantity |
50 µg (Variants) |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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Podoplanin
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Gene ID
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PDPN
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UniProt
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Q86YL7-3
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Immunogen
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The immunogen for anti-PDPN antibody: synthetic peptide directed towards the middle region of human PDPN
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Sequence
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VATSHSTEKVDGDTQTTVEKDGLSTVTLVGIIVGVLLAIG FIGAIIVVVM
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Cross-Reactivity
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Human
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-PDPN antibody concentration is 1 mg/ml.
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Description
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PDPN is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Characteristics
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Antigen Size: 238 amino acids
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Molecular Weight
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25kDa
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Application Notes
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WB Suggested Anti-PDPN Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Placenta.
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Restrictions
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For Research Use only
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Product
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Christou, Pearce, Watson et al.: "Renal cells activate the platelet receptor CLEC-2 through podoplanin." in: The Biochemical journal, Vol. 411, Issue 1, pp. 133-40, 2008 (PubMed).
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Alternatives for antigen "Podoplanin (PDPN)", type "Antibodies"
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Hosts
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Rabbit (41), Mouse (31), Rat (20), Syrian Hamster (9), Goat (3), Hamster (3), Sheep (1)
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Reactivities
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Human (61), Mouse (Murine) (40), Rat (Rattus) (20), Dog (Canine) (1)
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Applications
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Western Blotting (WB) (55), Flow Cytometry (FACS) (32), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (30), Immunofluorescence (IF) (24), Immunoprecipitation (IP) (19), ELISA (18), Immunohistochemistry (IHC) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (14), Immunocytochemistry (ICC) (6), Immunohistochemistry (Fixed) (IHC (fx)) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Fluorescence Microscopy (FM) (1), Immunoelectron Microscopy (IEM) (1), Intracellular Staining (IS) (1)
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Conjugates
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Alexa Fluor (8), PE (7), Biotin (4), FITC (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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C-Term (19), AA 38-51 (10), AA 1-206 (4), N-Term (4), Internal Region (2), Extracellular Domain (1)
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Alternatives 
