SPOCK3 antibody (Middle Region)

Catalog No. ABIN405715

This Rabbit Polyclonal antibody specifically detects SPOCK3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig and Rabbit.It has been mentioned in 1 publication

Quick Overview for SPOCK3 antibody (Middle Region) (ABIN405715)

Target: SPOCK3 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 3 (SPOCK3))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPOCK3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPOCK3 Antibody

Binding Specificity: Middle Region

Purpose: SPOCK3 Antibody - middle region

Sequence: CPCPSDKPTS TSRNVKRACS DLEFREVANR LRDWFKALHE SGSQNKKTKT

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SPOCK3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SPOCK3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44921-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-SPOCK3 antibody (ABIN405715)

Lutter, Xie, Tatin, Makinen: "Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation." in: The Journal of cell biology, Vol. 197, Issue 6, pp. 837-49, (2012) (PubMed).

Target Details for SPOCK3

Target: SPOCK3 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 3 (SPOCK3))

Alternative Name: SPOCK3

Background:

Background Information: Proteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK3 is a member of a novel Ca(2+)-binding proteoglycan familyProteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK3 encodes a member of a novel Ca(2+)-binding proteoglycan family.[supplied by OMIM].

Gene Name: Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

Alternative Symbols: TES-3, TICN3, HSAJ1454

Protein Name: Testican-3

Molecular Weight: 49kDa

Gene ID: 50859

NCBI Accession: NP_001035249

UniProt: B3KR67

Pathways: Glycosaminoglycan Metabolic Process