FCRLA antibody (C-Term)

Catalog No. ABIN406100

The Rabbit Polyclonal anti-FCRLA antibody has been validated for WB. It is suitable to detect FCRLA in samples from Human.

Quick Overview for FCRLA antibody (C-Term) (ABIN406100)

Target: FCRLA (Fc Receptor-Like A (FCRLA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCRLA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FCRLA Antibody

Binding Specificity: C-Term

Sequence: MPDPHLYHQM GLLLKHMQDV RVLLGHLLME LRELSGHRKP GTTKATAE

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against FCRLA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FCRLA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 376 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FCRLA

Target: FCRLA (Fc Receptor-Like A (FCRLA))

Alternative Name: FCRLA

Background: Receptors for the Fc fragment of IgG, or FCGRs, are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. FCRLA may be implicated in B-cell differentiation and lymphomagenesis.Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-742 BM471887.1 3-744 743-1338 BC006521.2 558-1153 1339-1684 BX112608.1 318-663 1685-2357 BX649184.1 2243-2915
Alias Symbols: FCRL, FCRLM1, FCRLX, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FREB, MGC4595, RP11-474I16.5, FCRX, FCRL1
Protein Size: 376

Molecular Weight: 41 kDa

Gene ID: 84824

NCBI Accession: NM_032738, NP_116127

UniProt: Q7L513