FBXL16 antibody (Middle Region)

Catalog No. ABIN406327

Product Details anti-FBXL16 Antibody

Target: FBXL16 (F-Box and Leucine-Rich Repeat Protein 16 (FBXL16))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL16 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GCPLLTTTGL SGLVQLQELE ELELTNCPGA TPELFKYFSQ HLPRCLVIE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against FBXL16. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXL16

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 479 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXL16

Target: FBXL16 (F-Box and Leucine-Rich Repeat Protein 16 (FBXL16))

Alternative Name: FBXL16 (FBXL16 Products)

Synonyms: C16orf22 antibody, Fbl16 antibody, c380A1.1 antibody, BC042620 antibody, Scirr1 antibody, VIER F-box proteine 2 antibody, F-box and leucine rich repeat protein 16 antibody, fbxl16, putative antibody, F-box and leucine-rich repeat protein 16 antibody, VIER F-box protein 2 antibody, FBXL16 antibody, Smp_174380 antibody, fbxl16 antibody, Fbxl16 antibody, VFB2 antibody

Background: FBXL16 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXL16, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: C16orf22, FLJ33735, Fbl16, MGC33974, c380A1.1
Protein Interaction Partner: HPCAL4, LATS2, MAPK6,
Protein Size: 479

Molecular Weight: 52 kDa

Gene ID: 146330

NCBI Accession: NM_153350, NP_699181

UniProt: Q8N461