F-Box and Leucine-Rich Repeat Protein 16 (FBXL16) (Middle Region) antibody

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Antigen
Synonyms C16orf22, Fbl16, c380A1.1, BC042620, Scirr1, VIER F-box proteine 2
Epitope
Middle Region
(10), (7), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(35), (21), (21)
Host
Rabbit
(35)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(25), (11), (9), (9), (7), (3), (2), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human FBXL16
Blocking Peptide Blocking peptide for this product available: F-Box and Leucine-Rich Repeat Protein 16 (FBXL16) (Middle Region) peptide (ABIN976713)
Sequence GCPLLTTTGL SGLVQLQELE ELELTNCPGA TPELFKYFSQ HLPRCLVIE
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Horse : 90 %
Characteristics This is a rabbit polyclonal antibody against FBXL16. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name FBXL16 (FBXL16 Antibody Abstract)
Background FBXL16 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXL16, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Molecular Weight 52 kDa
Gene ID 146330
NCBI Accession NM_153350, NP_699181
UniProt Q8N461
Research Area Proteolysis / Ubiquitin
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 479 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-F-Box and Leucine-Rich Repeat Protein 16 (FBXL16) (Middle Region) antibody (ABIN406327) WB Suggested Anti-FBXL16 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Martin, Han, Gordon et al.: "The sequence and analysis of duplication-rich human chromosome 16. ..." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004 (PubMed).

Catalog No. ABIN406327
$289.00
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