GNAI2 antibody (C-Term)

Catalog No. ABIN406411

This Rabbit Polyclonal antibody specifically detects GNAI2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Dog, Goat, Horse, Rabbit, Sheep and Zebrafish (Danio rerio).

Quick Overview for GNAI2 antibody (C-Term) (ABIN406411)

Target: GNAI2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Goat, Horse, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNAI2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GNAI2 Antibody

Binding Specificity: C-Term

Sequence: EYTGANKYDE AASYIQSKFE DLNKRKDTKE IYTHFTCATD TKNVQFVFDA

Predicted Reactivity: Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against GNAI2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GNAI2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 355 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GNAI2

Target: GNAI2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 2 (GNAI2))

Alternative Name: GNAI2

Background: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli.
Alias Symbols: GIP, GNAI2B, H_LUCA15.1, H_LUCA16.1
Protein Interaction Partner: NOTCH2NL, KRTAP10-8, KRT40, GPSM3, RGS20, UBC, TRIP6, MDFI, KRT31, SUMO2, RNF2, GCLM, GDI1, NAGK, SCRN1, LTB4R, ESR1, ATP4A, Rgs13, RGS3, PAN2, NPM1, NCF2, MTNR1A, HSP90AB1, HSP90AA1, CFTR, MYH10, GNB1, GNAI3, GNAI1, CYSTM1, ERGIC1, CORO1C, DHX30, SRSF1,
Protein Size: 355

Molecular Weight: 40 kDa

Gene ID: 2771

NCBI Accession: NM_002070, NP_002061

UniProt: P04899

Pathways: cAMP Metabolic Process, G-protein mediated Events, Thromboxane A2 Receptor Signaling