Pyridoxal (Pyridoxine, Vitamin B6) Phosphatase (PDXP) (Middle Region) antibody

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Antigen
Synonyms CIN, PLP, dJ37E16.5, 1600027H05Rik, AB041662, PLPP, Rbp1
Epitope
Middle Region
(12), (2), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(18), (4), (4), (2)
Host
Rabbit
(12), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(18), (12), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human PDXP
Blocking Peptide Blocking peptide for this product available: Pyridoxal (Pyridoxine, Vitamin B6) Phosphatase (PDXP) (Middle Region) peptide (ABIN981565)
Sequence DPWHPLSDGS RTPGTGSLAA AVETASGRQA LVVGKPSPYM FECITENFSI
Predicted Reactivity Dog : 100 %, Horse : 100 %, Mouse : 100 %, Rat : 90 %
Characteristics This is a rabbit polyclonal antibody against PDXP. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PDXP (PDXP Antibody Abstract)
Background Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP.Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 [PubMed 14522954]).
Molecular Weight 32 kDa
Gene ID 57026
NCBI Accession NP_064711, NM_020315
UniProt Q96GD0
Research Area Signaling, Metabolism
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 296 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Pyridoxal (Pyridoxine, Vitamin B6) Phosphatase (PDXP) (Middle Region) antibody (ABIN406629) WB Suggested Anti-PDXP Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Background publications Gohla, Birkenfeld, Bokoch: "Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics." in: Nature cell biology, Vol. 7, Issue 1, pp. 21-9, 2005 (PubMed).

Catalog No. ABIN406629
$289.00
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