ERG antibody (N-Term)

Catalog No. ABIN406640

The Rabbit Polyclonal anti-ERG antibody has been validated for WB. It is suitable to detect ERG in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) and Saccharomyces cerevisiae.

Quick Overview for ERG antibody (N-Term) (ABIN406640)

Target: ERG (ERG, ETS transcription factor (ERG))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERG Antibody

Binding Specificity: N-Term

Sequence: IMTKVHGKRY AYKFDFHGIA QALQPHPPES SLYKYPSDLP YMGSYHAHPQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against ERG. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ERG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 462 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ERG

Target: ERG (ERG, ETS transcription factor (ERG))

Alternative Name: ERG

Background: V-ets erythroblastosis virus E26 oncogene like isoform 2 (ERG) is a transcriptional regulator. It may participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.
Alias Symbols: erg-3, p55
Protein Interaction Partner: UBC, SFPQ, RPLP0, PRKDC, POLR2A, PCBP1, NUMA1, NPM1, NONO, NCL, ILF3, ILF2, HSPD1, HNRNPU, HNRNPH3, HNRNPH1, HNRNPF, HNRNPD, HNRNPC, HNRNPAB, HNRNPA2B1, HNRNPA1, FBL, ELAVL1, EEF1A2, DKC1, CLTC, CDC5L, HNRNPUL2, RCC2, PRPF40A, SF3B1, SF3B3, SNRNP200, PUF6
Protein Size: 462

Molecular Weight: 52 kDa

Gene ID: 2078

NCBI Accession: NM_004449, NP_004440

UniProt: P11308