ARP1 Actin-Related Protein 1 Homolog A, Centractin alpha (Yeast) (ACTR1A) antibody

Antigen: ARP1 Actin-Related Protein 1 Homolog A, Centractin alpha (Yeast) (ACTR1A)

Synonyms: ARP1, CTRN1, FLJ52695, FLJ52800, FLJ55002, Arp1, alpha-Arp1, ACTR1A, actr1a, MGC83436, arp1, ctrn1, centractin

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Xenopus laevis, Chicken, Zebrafish

Application: Western Blotting (WB)

Catalog no.: ABIN406684

Additional Information

Alternative name: Centractin alpha

Gene ID: ACTR1A

UniProt: P61163

Immunogen: The immunogen for anti-ACTR1A antibody: synthetic peptide directed towards the middle region of human ACTR1A

Sequence: AIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSR FRAPELLFRP

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Format: Lyophilized

Reconstitution: Add 50 µl of distilled water. Final anti-ACTR1A antibody concentration is 1 mg/ml.

Description: ACTR1A is a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Characteristics: Antigen Size: 376 amino acids

Molecular Weight: 41kDa

Application Details

Application Notes: WB Suggested Anti-ACTR1A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysate.

Purification: Affinity Purified

Buffer: PBS

Storage (Long Term): For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Storage (Short Term): Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.

Restrictions: For Research Use only

Images

WB Suggested Anti-ACTR1A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysate

Publications

Product: Sugarbaker, Richards, Gordon et al.: "Transcriptome sequencing of malignant pleural mesothelioma tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 9, pp. 3521-6, 2008 (PubMed).