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Antibodies
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anti-SRY (Sex Determining Region Y)-Box 8 (SOX8) antibody
SRY (Sex Determining Region Y)-Box 8 (SOX8) antibody
| Antigen |
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| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Dog (Canine), Human, Rat (Rattus), Mouse (Murine), Xenopus laevis
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Conjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
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Application
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| Catalog no. |
ABIN406765 |
| Quantity |
50 µg |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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SOX8
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Gene ID
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SOX8
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UniProt
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P57073
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Immunogen
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The immunogen for anti-SOX8 antibody: synthetic peptide directed towards the C terminal of human SOX8
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Sequence
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ASPTETGPPRPHIKTEQPSPGHYGDQPRGSPDYGSCSGQS SATPAAPAGP
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Cross-Reactivity
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Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-SOX8 antibody concentration is 1 mg/ml.
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Description
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SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).
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Characteristics
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Antigen Size: 446 amino acids
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Molecular Weight
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47kDa
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Application Notes
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WB Suggested Anti-SOX8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Hela cell lysate.
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Research Area
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Neurology
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Restrictions
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For Research Use only
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Product
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Wissmüller, Kosian, Wolf et al.: "The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors." in: Nucleic acids research, Vol. 34, Issue 6, pp. 1735-44, 2006 (PubMed).
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Alternatives for antigen "SRY (Sex Determining Region Y)-Box 8 (SOX8)", type "Antibodies"
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Hosts
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Rabbit (26), Goat (6), Mouse (1)
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Reactivities
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Human (28), Cow (Bovine) (18), Horse (Equine) (18), Mouse (Murine) (18), Rat (Rattus) (18)
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Applications
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Immunofluorescence (IF) (15), ELISA (14), Western Blotting (WB) (11), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
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Epitopes
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AA 203-217 (3), AA 247-258 (3), C-Term (1), Internal Region,AA 224-253 (1)
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