Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN406765

SRY (Sex Determining Region Y)-Box 8 (SOX8) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Reactivity
»Alternatives Dog (Canine), Human, Rat (Rattus), Mouse (Murine), Xenopus laevis
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN406765
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-SOX8 antibody: synthetic peptide directed towards the C terminal of human SOX8
Sequence ASPTETGPPRPHIKTEQPSPGHYGDQPRGSPDYGSCSGQS SATPAAPAGP
Cross-Reactivity Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
Predicted Reactivity Human : 100%, Bovine : 92%, Dog : 92%, Horse : 92%, Guinea pig : 85%, Rat : 85%, Mouse : 78%, African clawed frog : 76%
Characteristics Antigen Size: 446 amino acids
Purification Affinity Purified
Alternative Name SOX8
Background SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).
Molecular Weight 47kDa
Gene ID SOX8
UniProt P57073
Research Area Neurology
Application Notes WB Suggested Anti-SOX8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Hela cell lysate.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µl of distilled water
Buffer Final anti-SOX8 antibody concentration is 1 mg/ml.
Storage 4 °C
Storage Comment Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen. For longer periods of storage, store at -20°C
Background publications Wissmüller, Kosian, Wolf et al.: "The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors." in: Nucleic acids research, Vol. 34, Issue 6, pp. 1735-44, 2006 (PubMed).

Alternatives for antigen "SRY (Sex Determining Region Y)-Box 8 (SOX8)", type "Antibodies"
Hosts (24), (9), (7)
Reactivities (38), (15), (13), (12)
Applications (25), (20), (10), (3), (3), (1), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Beacon