HLA DQ antibody (Biotin)

Catalog No. ABIN452105

The Mouse Monoclonal anti-HLA DQ antibody is suitable to detect HLA DQ in samples from Human. It has been validated for FACS and IHC (fro).

Quick Overview for HLA DQ antibody (Biotin) (ABIN452105)

Target: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLA DQ antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: FN81

Product Details anti-HLA DQ Antibody (Biotin)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: HLA-DQ, HLA class II histocompatibility antigen DQ, MHC class II antigen DQ, majorhistocompatibility complex class II

Purification: Affinity Chromatography.

Immunogen: Stimulated human B lymphocytes. The antigen is HLA-DQ. The epitope has not been further characterized.

Isotype: IgG2a

Application Details

Application Notes: Immunohistochemistry on Frozen Sections:
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 0.5 mL distilled water (= Stock solution).

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, with 0.05 % Kathon as preservative and 5 mg/mL BSA as stabilizer.

Preservative: Kathon CG

Precaution of Use: This product contains Kathon CG a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C. Stock solution or aliquots of stock solution can be kept frozen at -20 °C. Do not freeze working dilutions. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for HLA DQ

Target: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Alternative Name: HLA Class II DQ

Background: HLA-DQ is an HLA class II antigen with homology to murine H-2A. HLA class II antigens are mainly expressed on specialized antigen presenting cells (APCs), dendritic cells, B-cells and macrophages. HLA class II antigen is presented on activated T-cells. HLA class II molecules present exogenously derived antigen to the T-cell receptor (TCR) on CD4+ T lymphocytes. Both chains in HLA-DQ are polymorphic. HLA-DQ is expressed after DR and DP during haemotopoietic progenitor cell development. It is strongly expressed in the thymic cortex.Synonyms: MHC Class II DQ