PARD3 antibody (C-Term)

Catalog No. ABIN453777

Product Details anti-PARD3 Antibody

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARD3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to PARD3.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human PARD3

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PARD3

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Alternative Name: PARD3 / PAR3 (PARD3 Products)

Synonyms: ASIP antibody, Baz antibody, PAR3 antibody, PAR3alpha antibody, PARD-3 antibody, PARD3A antibody, SE2-5L16 antibody, SE2-5LT1 antibody, SE2-5T2 antibody, Par3 antibody, AA960621 antibody, AI256638 antibody, D8Ertd580e antibody, PAR-3 antibody, Pard3a antibody, asip antibody, bazooka antibody, par-3 antibody, par3 antibody, pard3 antibody, par-3 family cell polarity regulator antibody, partitioning defective 3 homolog antibody, par-3 family cell polarity regulator alpha, b antibody, par-3 family cell polarity regulator S homeolog antibody, PARD3 antibody, Pard3 antibody, LOC100551156 antibody, LOC100473914 antibody, pard3 antibody, pard3ab antibody, pard3.S antibody

Background: PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs, see MIM 606057) and GTPase-activating proteins (GAPs, see MIM 604980), interacts with a large set of effector proteins that typically contain a CDC42/RAC (MIM 602048)-interactive binding (CRIB) domain.Synonyms: ASIP, Atypical PKC isotype-specific-interacting protein, CTCL tumor antigen se2-5, PAR-3, PAR3-alpha, PAR3A, PARD-3, Partitioning defective 3 homolog

Gene ID: 56288

NCBI Accession: NP_062565

UniProt: Q8TEW0

Pathways: Cell-Cell Junction Organization