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Vascular Cell Adhesion Molecule 1 (VCAM1) antibody (APC)

Antigen

Vascular Cell Adhesion Molecule 1 (VCAM1)

Synonyms CD106, MGC99561, INCAM-100, DKFZp779G2333, Vcam-1, VCAM1B, MGC108734, VCAM1, fi76d06, wu:fi76d06, zgc:158875, VCAM-1, DKFZp469N1820
Clonality Monoclonal (STA)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Conjugate
Catalog no. ABIN457311
Quantity 100 tests
Price 377.00 $   Plus shipping costs $35.00
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Additional Information

Alternative name CD106
Immunogen Human DS6 T cell line
Isotype IgG1
Clone STA
Description CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesionmolecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule takingpart in their positive selection and survival, as well as in adhesion, transendothelial migrationand activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts.Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation,tumour cells can use overexpressed VCAM-1 to escape T cell immunity. Soluble form ofVCAM-1 (sVCAM-1) is an inflammatory marker and can be used also in prognosis ofsubsequent cariovascular events following acute coronary syndromes.
Specificity The mouse monoclonal antibody STA recognizes CD106 antigen (VCAM-1), a 100-110 kDatype I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyteadhesion, and a costimulation molecule.HLDA V, WS Code A013

Application Details

Research Area CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Vascular Cell Adhesion Molecule 1 (VCAM1)", type "Antibodies"
Hosts Mouse (114), Rat (62), Rabbit (26), Sheep (2)
Reactivities Human (124), Mouse (Murine) (81), Rat (Rattus) (29), Monkey (5), Pig (Porcine) (5), Dog (Canine) (4), Chicken (2), Cow (Bovine) (2), Horse (Equine) (2), Rabbit (2)
Applications Flow Cytometry (FACS) (159), Immunohistochemistry (Frozen Sections) (IHC (fro)) (57), Immunoprecipitation (IP) (48), Western Blotting (WB) (38), Immunofluorescence (IF) (35), ELISA (30), Immunohistochemistry (IHC) (24), Functional Studies (Func) (21), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13), Enzyme Immunoassay (EIA) (11), Blocking Antibody (Inhibition) (4), Blocking Antibody (Inhibition) (3), Immunocytochemistry (ICC) (3), ELISA (Detection) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Biotin (30), FITC (27), PE (17), RPE (4), APC (1), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)