CD2 Molecule (CD2) antibody
| Antigen |
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| Synonyms |
T11, SRBC, FLJ46032, CD2, MGC140284, CD2R, LFA2, OX34, LFA-2, OX-34, Ly37, Ly-37 |
| Clonality |
Monoclonal (LT2) |
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Host
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Reactivity
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Human (147), Mouse (Murine) (53), Rat (Rattus) (46), Horse (Equine) (18), Pig (Porcine) (18), Dog (Canine) (15), Cow (Bovine) (10), Sheep (Ovine) (6), Monkey (4), Chicken (1), Goat (1)
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Application
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 Alternatives Flow Cytometry (FACS), Immunoprecipitation (IP)
Flow Cytometry (FACS) (192), Immunohistochemistry (Frozen Sections) (IHC (fro)) (57), Immunoprecipitation (IP) (50), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (44), Western Blotting (WB) (23), Immunofluorescence (IF) (22), Functional Studies (Func) (18), ELISA (7), ELISA (Detection) (5), Immunocytochemistry (ICC) (4), Cytotoxicity Test (CyTox) (2), Enzyme Immunoassay (EIA) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1), To be determined by user (TBD) (1)
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| Catalog no. |
ABIN457428 |
| Quantity |
0.1 mg (1 mg/ml) |
| Price |
260.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 3 to 5 Business Days |
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Alternative name
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CD2
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Immunogen
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Normal human blood lymphocytes.
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Format
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Purified
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Isotype
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IgG2a (Matching secondary antibodies)
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Clone
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LT2
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Description
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CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interactionwith CD58 stabilizes adhesion between T cells and antigen presenting or target cells.Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within thetwo-dimensional cell-cell interface to provide tight adhesion. Morover, T cell activationinduces increased CD2 expression and its lateral mobility, making easier contact betweenCD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites ofcell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reducesintestinal inflammation and helps to control infection.
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Specificity
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The antibody LT2 reacts with CD2, a 50 kDa glycoprotein present on the human peripheralblood T lymphocytes and NK cells, also expressed by all thymocytes.HLDA VI, WS Code T 6T-008
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Alternatives for antigen "CD2 Molecule (CD2)", type "Antibodies"
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Hosts
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Mouse (168), Rat (40), Rabbit (25)
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Reactivities
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Human (147), Mouse (Murine) (53), Rat (Rattus) (46), Horse (Equine) (18), Pig (Porcine) (18), Dog (Canine) (15), Cow (Bovine) (10), Sheep (Ovine) (6), Monkey (4), Chicken (1), Goat (1)
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Applications
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Flow Cytometry (FACS) (192), Immunohistochemistry (Frozen Sections) (IHC (fro)) (57), Immunoprecipitation (IP) (50), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (44), Western Blotting (WB) (23), Immunofluorescence (IF) (22), Functional Studies (Func) (18), ELISA (7), ELISA (Detection) (5), Immunocytochemistry (ICC) (4), Cytotoxicity Test (CyTox) (2), Enzyme Immunoassay (EIA) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1), To be determined by user (TBD) (1)
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Conjugates
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FITC (29), Biotin (25), PE (23), RPE (8), APC (7), Alexa Fluor 488 (3), PE,Cy5 (3), Alexa Fluor 647 (2), Cy5,PE (2), DY647 (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), Alexa Fluor 700 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Dyomics 647 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5.5 (1), PE,Cy7 (1), Pacific Blue (1), RBITC (1), RPE,Cy5 (1)
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