Cytokeratin 8/18 antibody
Quick Overview for Cytokeratin 8/18 antibody (ABIN472492)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Specificity
- Recognizes human cytokeratins with molecular weights 52 and 45kD, corresponding to cytokeratins 8 and 18, respectively. Useful in the detection of adenocarcinomas, mesotheliomas and certain squamous epithelia-derived carcinomas. Interestingly, some epithelial tumors demonstrate cytokeratin 8 and 18 expression, but normal strati ed squamous epithelium does not.
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Purification
- Purified
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Immunogen
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Human keratin 8 alpha 18. Expected Staining Pattern: Cytoplasmic and membrane.
Type of Immunogen: Purified protein -
Isotype
- IgG1
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Application Notes
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Approved: IHC, IHC-Fr, IHC-P
Usage: Suitable for use in Immunohistochemistry. Immunohistochemistry: Stains cytokeratins 8 and 18 in frozen tissue or formalin-fixed, paraffin-embedded (FFPE) tissue sections. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 1 % BSA, 0.1 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Cytokeratin 8/18
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Alternative Name
- Cytokeratin 8+18
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Background
- This antibody detects: Cytokeratin 8+18
Target
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