AE Binding Protein 2 (AEBP2) (C-Term) antibody

Details for Product No. ABIN486849
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Antigen
Synonyms wu:fk42f11, wu:fk52h12, zgc:63755, AU023766, B230313N05Rik
Epitope
C-Term
(10), (7), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Xenopus laevis, Zebrafish (Danio rerio), Human
(18), (5), (3)
Host
Rabbit
(16), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(17), (11), (2)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN486849
289.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human AEBP2
Sequence FDAQTLDAIR HRAICFNLSA HIESLGKGHS VVFHSTVIAK RKEDSGKIKL
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against AEBP2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name AEBP2
Background AEBP2 is a DNA-binding transcriptional repressor. It may interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3.
Molecular Weight 33 kDa
Gene ID 121536
NCBI Accession NP_694939, NM_153207
UniProt Q6ZN18
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 295 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-AE Binding Protein 2 (AEBP2) (C-Term) antibody WB Suggested Anti-AEBP2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Muscle
Background publications Cao, Zhang: "SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex." in: Molecular cell, Vol. 15, Issue 1, pp. 57-67, 2004 (PubMed).

Validation Images
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