TFAP2E antibody (N-Term)

Catalog No. ABIN486888

This anti-TFAP2E antibody is a Rabbit Polyclonal antibody detecting TFAP2E in WB. Suitable for Human, Mouse and Cow.

Quick Overview for TFAP2E antibody (N-Term) (ABIN486888)

Target: TFAP2E (Transcription Factor AP-2 epsilon (Activating Enhancer Binding Protein 2 Epsilon) (TFAP2E))

Reactivity: Human, Mouse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFAP2E antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TFAP2E Antibody

Binding Specificity: N-Term

Sequence: MLVHTYSAME RPDGLGAAAG GARLSSLPQA AYGPAPPLCH TPAATAAAEF

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 92%

Characteristics: This is a rabbit polyclonal antibody against TFAP2E. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TFAP2E

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 442 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFAP2E

Target: TFAP2E (Transcription Factor AP-2 epsilon (Activating Enhancer Binding Protein 2 Epsilon) (TFAP2E))

Alternative Name: TFAP2E

Background: TFAP2E is the sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 epsilon may play a role in the development of the CNS and in cartilage differentiation
Alias Symbols: AP2E, MGC49007
Protein Interaction Partner: UBC,
Protein Size: 442

Molecular Weight: 46 kDa

Gene ID: 339488

NCBI Accession: NM_178548, NP_848643

UniProt: Q6VUC0