PSMD11 antibody (N-Term)

Catalog No. ABIN486924

Cited in 1 publication. The Rabbit Polyclonal anti-PSMD11 antibody (ABIN486924) specifically detects PSMD11 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Horse, Guinea Pig and Rabbit samples.

Quick Overview for PSMD11 antibody (N-Term) (ABIN486924)

Target: PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PSMD11 Antibody

Binding Specificity: N-Term

Sequence: MAAAAVVEFQ RAQSLLSTDR EASIDILHSI VKRDIQENDE EAVQVKEQSI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against PSMD11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSMD11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 422 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PSMD11 antibody (ABIN486924)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for PSMD11

Target: PSMD11 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 11 (PSMD11))

Alternative Name: PSMD11

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits a
Alias Symbols: MGC3844, S9, p44.5, Rpn6
Protein Interaction Partner: HUWE1, SUMO2, SUMO3, PSMD14, UBC, MDM2, ASB11, SHFM1, PSMC2, PSMC1, RPS8, PSMD12, PSMD8, PSMD3, PSMD1, PSMC6, PSMC5, KCMF1, PRMT6, UCHL5, KIAA0368, ADRM1, RPS21, RPS15A, PARK2, RNF11, NOS2, SMAD5, SMAD4, SMAD3, SMAD2, SMAD1, FN1, CFTR, VCAM1, LRRK2, env,
Protein Size: 422

Molecular Weight: 47 kDa

Gene ID: 5717

NCBI Accession: NM_002815, NP_002806

UniProt: O00231

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway