POU3F3 antibody (N-Term)

Catalog No. ABIN487007

The Rabbit Polyclonal anti-POU3F3 antibody has been validated for WB. It is suitable to detect POU3F3 in samples from Human, Mouse and Rat.

Quick Overview for POU3F3 antibody (N-Term) (ABIN487007)

Target: POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU3F3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POU3F3 Antibody

Binding Specificity: N-Term

Sequence: GGGGGGGGGA GGGGGGMQPG SAAVTSGAYR GDPSSVKMVQ SDFMQGAMAA

Predicted Reactivity: Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against POU3F3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human POU3F3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 500 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for POU3F3

Target: POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

Alternative Name: POU3F3

Background: POU3F3 is the transcription factor that acts synergistically with SOX11 and SOX4. POU3F3 plays a role in neuronal development. POU3F3 is implicated in an enhancer activity at the embryonic met-mesencephalic junction, the enhancer element contains the octamer motif (5'-ATTTGCAT-3').POU3F3 is a member of the class III POU family of transcription factors (see POU3F1, MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences Sumiyama et al. (1996) [PubMed 8703082].[supplied by OMIM].
Alias Symbols: BRN1, OTF8
Protein Interaction Partner: Dlg4, SOX8, PPP1R15A, SOX10, SOX11, POU3F4,
Protein Size: 500

Molecular Weight: 50 kDa

Gene ID: 5455

NCBI Accession: NM_006236, NP_006227

UniProt: P20264