DMPK antibody (Middle Region)

Catalog No. ABIN487179

Cited in 1 publication. The Rabbit Polyclonal anti-DMPK antibody (ABIN487179) specifically detects DMPK in WB and IHC. The antibody is reactive with Human, Rat, Mouse, Cow, Dog, Guinea Pig and Horse samples.

Quick Overview for DMPK antibody (Middle Region) (ABIN487179)

Target: DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMPK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DMPK Antibody

Binding Specificity: Middle Region

Purpose: DMPK Antibody - middle region

Sequence: TRLGRGGAGD FRTHPFFFGL DWDGLRDSVP PFTPDFEGAT DTCNFDLVED

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DMPK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DMPK

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42183-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-DMPK antibody (ABIN487179)

Ramasamy, Ren, Mench, Regan: "Impact of initial biofilm growth on the anode impedance of microbial fuel cells." in: Biotechnology and bioengineering, Vol. 101, Issue 1, pp. 101-8, (2008) (PubMed).

Target Details for DMPK

Target: DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

Alternative Name: DMPK

Background:

Background Information: The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium chann

Gene Name: Dystrophia myotonica-protein kinase

Alternative Symbols: DM, DM1, DMK, MDPK, DM1PK, MT-PK

Protein Name: Myotonin-protein kinase

Molecular Weight: 69 kDa

Gene ID: 1760

NCBI Accession: NP_004400

UniProt: Q09013

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development