Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (N-Term) antibody

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Antigen
Synonyms TRPV5, CAT2, D630033B11, ECAC1, OTRPC3, CaT2, Ecac1, ECAC
Epitope
N-Term
(21), (16), (6), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
(65), (27), (23), (4), (4), (3), (2), (1)
Host
Rabbit
(48), (16), (7), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(63), (35), (15), (11), (11), (8), (3), (3), (3), (2)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human TRPV5
Sequence MLQQKRILES PLLRASKEND LSVLRQLLLD CTCDVRQRGA LGETALHIAA
Predicted Reactivity Human : 100 %, Pig : 90 %, Bovine : 80 %, Dog : 80 %, Guinea pig : 80 %, Mouse : 80 %, Rat : 80 %, Horse : 70 %, Rabbit : 70 %
Characteristics This is a rabbit polyclonal antibody against TRPV5. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TRPV5 (TRPV5 Antibody Abstract)
Background TRPV5 is a member of the transient receptor family and the TrpV subfamily. TRPV5, a calcium-selective channel, has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. TRPV5 forms homotetramers or heterotetramers and is activated by a low internal calcium level.This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.
Molecular Weight 82 kDa
Gene ID 56302
NCBI Accession NP_062815, NM_019841
UniProt Q9NQA5
Research Area Signaling, Metabolism
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 729 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (N-Term) antibody (ABIN487228) WB Suggested Anti-TRPV5 Antibody Titration: 0.2-1 ug/ml
Positive Control...
Western Blotting (WB) image for anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (N-Term) antibody (ABIN487228) Sample Type: 1-4. hRetinal pigment epithelial cells, 4 individual donors (20ug...
Immunohistochemistry (IHC) image for anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (N-Term) antibody (ABIN487228) Sample Type: hRetinal pigment epithelial cells
Green: primary
...
Western Blotting (WB) image for anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (N-Term) antibody (ABIN487228) WB Suggested Anti-TRPV5
Antibody Titration: 0.2-1 µg/mL
Positive Contro...
Product cited in: Cha, Wu, Huang: "Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5." in: American journal of physiology. Renal physiology, Vol. 294, Issue 5, pp. F1212-21, 2008 (PubMed).

Catalog No. ABIN487228
$289.00
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