MAPRE3 antibody (Internal Region)

Catalog No. ABIN487989

The Goat Polyclonal anti-MAPRE3 antibody (ABIN487989) specifically detects MAPRE3 in WB and EIA. The antibody is reactive with Human, Mouse, Cow and Dog samples.

Quick Overview for MAPRE3 antibody (Internal Region) (ABIN487989)

Target: MAPRE3 (Microtubule-Associated Protein, RP/EB Family, Member 3 (MAPRE3))

Reactivity: Human, Mouse, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This MAPRE3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-MAPRE3 Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to MAPRE3.

Cross-Reactivity (Details): Species reactivity (expected):Canine, Bovine.
Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography

Immunogen: Peptide with sequence SGRLSNVAPPCILR, from the internal region of the protein sequence according to NP_036458.2.

Application Details

Application Notes: Peptide ELISA: 1/64000. Western blot: Approx 32 kDa band observed in Human Brain (Cerebellum and Amygdala)and Mouse Brain lysates (calculated MW of 32 kDa according to NP_036458.2). Recommended concentration: 0.1 - 1.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for MAPRE3

Target: MAPRE3 (Microtubule-Associated Protein, RP/EB Family, Member 3 (MAPRE3))

Alternative Name: MAPRE3

Background: EB3 is a 282 amino acid homologue of EB1, a protein known to bind Adenomatous Polyposis Coli. It has been shown to bind to tubulin in vitro and microtubules in vivo. Northern blotting shows expressions to be mainly in brain, and to a lesser degree in muscle. EB3 interacts with APCL, a homologue of the tumor suppressor APC, and this interaction may be involved in the stabilization or extension of microtubules.Synonyms: EB1 protein family member 3, EB3, End-binding protein 3, Microtubule-associated protein RP/EB family member 3, RP3

Gene ID: 22924

NCBI Accession: NP_036458

UniProt: Q9UPY8