BAK1 antibody (AA 29-187)

Catalog No. ABIN492385

The Mouse Monoclonal anti-BAK1 antibody (Clone AT8B4) (ABIN492385) specifically detects BAK1 in WB, IF and EIA. The antibody is reactive with Human and Mouse samples.

Quick Overview for BAK1 antibody (AA 29-187) (ABIN492385)

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This BAK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Clone: AT8B4

Product Details anti-BAK1 Antibody

Binding Specificity: AA 29-187

Specificity: The antibody recognizes Human and Mouse BAK1. Other species not tested.

Characteristics: Synonyms: BAK1, BAK, BCL2L7, Bcl2-L-7, CDN1, Bcl-2 homologous antagonist/killer, Apoptosisregulator BAK, Bcl-2-like protein 7, cell death inhibitor 1

Purification: Protein-G Affinity Chromatography

Immunogen: Recombinant human BAK1 (29-187aa) purified from E. coli

Isotype: IgG2a

Application Details

Application Notes: ELISA. Western blot (1: 250-1: 500). Immunofluorecence (1: 250-1: 500).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for BAK1

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Alternative Name: Bcl-2-Like 7

Background: BAK1 encodes an receptor-like kinase (RLK) with a putative extracellular domain, a single transmembrane domain, an intracellular-juxtamembrane domain, and a kinase domain. BAK1 expression is associated with the progression of Prostate cancer (CaP). BAK1 appears to function in distinct receptor-signaling complexes to integrate multiple microbe-associated molecular pattern (MAMP) perception into downstream-signaling events. BAK1 can serve multiple purposes to simultaneously modulate MAMP-receptor complexes, BR signaling, and cell death for the benefit of bacterial infection, life style, and fitness.Synonyms: Apoptosis regulator BAK, BAK, BAK1, BCL2L7, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 7, Bcl2-L-7, CDN1, cell death inhibitor 1

Gene ID: 578

UniProt: Q16611

Pathways: Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response