USP2 antibody (C-Term)

Catalog No. ABIN498011

The Rabbit Polyclonal anti-USP2 antibody is suitable to detect USP2 in samples from Human and Mouse. It has been validated for IHC (p).

Quick Overview for USP2 antibody (C-Term) (ABIN498011)

Target: USP2 (Ubiquitin Specific Peptidase 2 (USP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-USP2 Antibody

Binding Specificity: C-Term

Specificity: Reacts with Ubiquitin Specific Protease 2 (USP2).

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated corresponding to C-terminal domain of Human USP2 .Remarks: Mouse Identity: 100% Mouse Similarity: 100%

Application Details

Application Notes: Immunohistochemistry on Formalin Fixed Paraffin Embedded Tissues: 5 μg/mL (Requirespretreatment with Proteinase K).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Target Details for USP2

Target: USP2 (Ubiquitin Specific Peptidase 2 (USP2))

Alternative Name: USP2

Background: UBP, an ubiquitin-specific protease, is selectively up regulated in bone by the osteotropic agents PTH, PTHrP and PGE2 and possibly via the PKA/cAMP pathway. It is also thought to play a role in the recycling of ubiquitin by hydrolysis of branched poly-ubiquitin from linear poly-ubiquitin chains, production of free ubiquitin from linear poly-ubiquitin chains and from certain ribosomal ubiquitin fusion proteins.Synonyms: 2UBP41, 41 kDa ubiquitin-specific protease, Deubiquitinating enzyme 2, Ubiquitin carboxyl-terminal hydrolase, Ubiquitin thioesterase 2, Ubiquitin-specific-processing protease 2

Gene ID: 9099

NCBI Accession: NP_004196

UniProt: O75604