ALDH3A1 antibody (C-Term)
Quick Overview for ALDH3A1 antibody (C-Term) (ABIN498081)
Target
See all ALDH3A1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Cross-Reactivity (Details)
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Species reactivity (expected):Human.
Species reactivity (tested):Mouse. -
Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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Immunogen
- Peptide with sequence C-RYPPSPAKMTQH, from the C Terminus of the protein sequence according to NP_000682.3. Genename: ALDH3A1
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Application Notes
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Peptide ELISA: Detection Limit: 1/32000. Western blot: 0.01-0.03 μg/mL. Detects a band of Approx 55 kDa in Mouse Eye lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ALDH3A1 (Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))
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Alternative Name
- ALDH3
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Background
- Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. ALDH3A1 forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. The enzyme is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea.Synonyms: ALDH3A1, ALDHIII, Aldehyde dehydrogenase, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase family 3 member A1, dimeric NADP-preferring
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Molecular Weight
- 50.5kDa according to Mouse NP_031462.2
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Gene ID
- 10090
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UniProt
- P47739
Target
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