Ephrin A1 antibody

Catalog No. ABIN498276

Product Details anti-Ephrin A1 Antibody

Target: Ephrin A1 (EFNA1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of Ephrin-A1 protein.

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity-chromatography using epitope-specific immunogen.

Application Details

Application Notes: Western blot: 1/500-1/1000. Immunoflourescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2 with 15 mM Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Ephrin A1

Target: Ephrin A1 (EFNA1)

Alternative Name: Ephrin-A1 (EFNA1 Products)

Synonyms: Xefrin-A1 antibody, b61 antibody, ecklg antibody, efl1 antibody, efna1 antibody, efna1a antibody, elfa-a antibody, epha1 antibody, eplg1 antibody, lerk1 antibody, tnfaip4 antibody, xelf-a' antibody, xelfa antibody, AI325262 antibody, B61 antibody, Efl1 antibody, Epl1 antibody, Eplg1 antibody, Lerk1 antibody, ECKLG antibody, EFL1 antibody, EPLG1 antibody, LERK-1 antibody, LERK1 antibody, TNFAIP4 antibody, efna1b antibody, MGC130661 antibody, ephrin-A1 S homeolog antibody, ephrin-A1 antibody, ephrin A1 antibody, ephrin-A1b antibody, ephrin-A1 L homeolog antibody, efna1.S antibody, efna1 antibody, EFNA1 antibody, efna1b antibody, Efna1 antibody, efna1.L antibody

Background: The Eph subfamily represents the largest group of receptor protein kinases identified to date. There is increasing evidence that Eph family members are involved in central nervous system function and in development. Ligands for Eph receptors include ephrin-A1 (LERK-1/B61), identified as a ligand for the EphA2 (Eck) receptor, ephrin-A2 (ELF-1), identified as a ligand for the EphA3 and EphA4 (Sek) receptors, ephrin-A3 (LERK-3), identified as a ligand for EphA5 (Ehk1) and EphA3 (Hek) receptors, ephrin-A4 (LERK-4), identified as a ligand for the EphA3 receptor, ephrin-A5 (AL-1), identified as a ligand for EphA5 (REK7), ephrin-B1 (LERK-2), identified as a ligand for the EphB1 (Elk) and EphB2 (Cek5) receptors, ephrin-B2 (LERK-5), identified as a ligand for the EphB1, EphB3 (Cek10) and EphB2 receptors, and ephrin-B3 (LERK-8), identified as a ligand for EphB1.Synonyms: EFNA1, EPH-related receptor tyrosine kinase ligand 1, EPLG1, Immediate early response protein B61, LERK-1, LERK1, TNFAIP4, Tumor necrosis factor, alpha-induced protein 4

Molecular Weight: approx. 23 kDa

Gene ID: 1942

NCBI Accession: NP_004419

UniProt: P20827

Pathways: RTK Signaling