DEFa3 antibody

Catalog No. ABIN498477

The Rabbit Polyclonal anti-DEFa3 antibody (ABIN498477) specifically detects DEFa3 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for DEFa3 antibody (ABIN498477)

Target: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEFa3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DEFa3 Antibody

Specificity: This antibody detects endogenous levels of Defensin alpha-3 protein. (region surrounding Ser52)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DEFa3

Target: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Alternative Name: Defensin alpha 3

Background: Defensins are a group of cyclic peptides containing 29-35 amino acids, which comprise approximately 30 % of the total protein content of neutrophil azurophilic granules. Various functions have been reported for the defensins, including antibacterial and antifungal activity and chemotactic activity for monocytes.Synonyms: DEF3, DEFA3, HNP-3, HP3, Neutrophil defensin 3

Gene ID: 1668

NCBI Accession: NP_005208

UniProt: P59666

Pathways: Cellular Response to Molecule of Bacterial Origin