CNPase (CNP) antibody
| Antigen |
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| Synonyms |
CNP1, Cnp1, Cnp-1, CNPase, CNPF, CNPI, CNPII, CNP, sb:cb662, wu:fd44a05, wu:fi35d08, si:ch73-158e11.4, DKFZp469F1421 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN498484 |
| Quantity |
100 µg (1,0 mg/ml) (Variants) |
| Price |
340.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: CNP, CNP1, Oligodendrocyte Marker, 2', 3'-cyclic-nucleotide 3'-phosphodiesterase
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Alternative name
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CNPase
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Gene ID
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1267
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Swiss-Prot
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P09543
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Cross-Reactivity
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Human, Mouse (Murine), Rat (Rattus)
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Description
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2’: 3’-cyclic nucleotide-3’-phosphodiesterase (CNPase) is a membrane-bound enzyme thatcan link tubulin to membranes and may regulate cytoplasmic microtubule distribution. CNPase acts as a microtubule-associated protein by promoting microtubule assembly, thisactivity resides in the C-terminus of the enzyme. CNPase is firmly associated with tubulinfrom brain tissue and thyroid cells and can be found at high concentrations in centralnervous system Myelin and in the outer segments of photoreceptors in the retina. Acutelead intoxication leads to disturbances in CNPase activity and the morphology of Myelin.
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Specificity
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CNPase pAb detects endogenous levels of CNPase protein. Species: Human, Mouse, Rat. Others not tested.
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Application Notes
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Western Blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1,0 mg/ml
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Purification
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Aff - Purified
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Buffer
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Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Neurology, Glia marker
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Restrictions
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For Research Use only
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Alternatives for antigen "CNPase (CNP)", type "Antibodies"
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Hosts
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Rabbit (12), Mouse (4), Chicken (1)
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Reactivities
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Human (16), Mouse (Murine) (8), Rat (Rattus) (8), Rabbit (2), Sheep (Ovine) (2), Cat (Feline) (1), Cow (Bovine) (1), Dog (Canine) (1), Pig (Porcine) (1)
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Applications
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Western Blotting (WB) (15), ELISA (Detection) (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), ELISA (2), Enzyme Immunoassay (EIA) (2), Immunofluorescence (IF) (2), ELISA (Capture) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)
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Epitopes
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AA 68-84 (1)
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Alternatives 
