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ACIN1 antibody

ACIN1 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499203
  • Target See all ACIN1 Antibodies
    ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))
    Reactivity
    • 40
    • 22
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 36
    • 4
    Rabbit
    Clonality
    • 36
    • 4
    Polyclonal
    Conjugate
    • 33
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACIN1 antibody is un-conjugated
    Application
    • 31
    • 19
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    Acinus antibody was raised against a peptide corresponding to amino acids 994 to 1009 of human AcinusL, 267 to 282 of human AcinusS', or 236 to 251 of human AcinusS, which are identical to those of mouse Acinus. The selected antigenic sequence is located near the N-terminus of active peptide p17.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    Human Acinus Peptide
    Isotype
    IgG
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    Discover our top product ACIN1 Primary Antibody
  • Application Notes
    ELISA. Western Blot: Acinus antibody can be used for detection of acinus at 0.5 to 1 μg/mL. Anapproximate 220 kDa band can be detected.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))
    Alternative Name
    Acinus / ACIN1 (ACIN1 Products)
    Synonyms
    acinus antibody, acinusb antibody, fi14c05 antibody, wu:fe06a10 antibody, wu:fi14c05 antibody, acinusa antibody, acinusl antibody, ik:tdsubc_2g5 antibody, si:zc14a17.12 antibody, wu:fb04g06 antibody, wu:fb40f03 antibody, wu:fb68h03 antibody, wu:fb80f07 antibody, wu:fc12e10 antibody, xx:tdsubc_2g5 antibody, acn antibody, ACINUS antibody, ACN antibody, fSAP152 antibody, 2610036I19Rik antibody, 2610510L13Rik antibody, Acinus antibody, Acn antibody, C79325 antibody, acinusL antibody, acinusS antibody, mKIAA0670 antibody, apoptotic chromatin condensation inducer 1b antibody, apoptotic chromatin condensation inducer 1a antibody, apoptotic chromatin condensation inducer 1 antibody, apoptotic chromatin condensation inducer 1 S homeolog antibody, acin1b antibody, acin1a antibody, acin1 antibody, ACIN1 antibody, acin1.S antibody, Acin1 antibody
    Background
    Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE (1). A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS (2)Synonyms: Apoptotic chromatin condensation inducer in the nucleus, KIAA0670
    Gene ID
    22985
    UniProt
    Q9UKV3
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