CCDC134 antibody (N-Term)

Catalog No. ABIN499587

The Rabbit Polyclonal anti-CCDC134 antibody (ABIN499587) specifically detects CCDC134 in WB, IHC (p) and EIA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CCDC134 antibody (N-Term) (ABIN499587)

Target: CCDC134 (Coiled-Coil Domain Containing 134 (CCDC134))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC134 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-CCDC134 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to CCDC134.

Purification: Affinity chromatography purified via peptide column

Immunogen: CCDC134 antibody was raised against a 17 amino acid peptide near the amino terminus of human CCDC134.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: CCDC134 antibody can be used for detection of CCDC134 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for CCDC134

Target: CCDC134 (Coiled-Coil Domain Containing 134 (CCDC134))

Alternative Name: CCDC134

Background: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.Synonyms: Coiled-coil domain-containing protein 134

Gene ID: 79879

NCBI Accession: NP_079097

UniProt: Q9H6E4