C1QTNF3 antibody (Intermediate Domain)

Catalog No. ABIN499667

The Rabbit Polyclonal anti-C1QTNF3 antibody has been validated for WB, IF and IHC (p). It is suitable to detect C1QTNF3 in samples from Human and Mouse.

Quick Overview for C1QTNF3 antibody (Intermediate Domain) (ABIN499667)

Target: C1QTNF3 (C1q and Tumor Necrosis Factor Related Protein 3 (C1QTNF3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QTNF3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C1QTNF3 Antibody

Binding Specificity: Intermediate Domain

Specificity: CTRP3 antibody was raised against a 16 amino acid peptide from near the center of human CTRP3.

Purification: Affinity chromatography purified via peptide column

Immunogen: Human CTRP3 / CORS26 (Intermediate Domain) Peptide

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: CTRP3 antibody can be used for the detection of CTRP3 by Western blot at 1 -2 μg/mL. Mouse heart cell lysate can be used as positive control. These proteins are oftenhighly modified post-translationally and migrate in SDS-PAGE at positions other than theirpredicted size. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for C1QTNF3

Target: C1QTNF3 (C1q and Tumor Necrosis Factor Related Protein 3 (C1QTNF3))

Alternative Name: C1QTNF3

Background: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development (5).Synonyms: C1ATNF3, CORS26, CTRP3, Complement C1q tumor necrosis factor-related protein 3, Secretory protein CORS26

Gene ID: 114899

NCBI Accession: NP_852100

UniProt: Q9BXJ4