C1QTNF3 antibody (AA 90-140)

Catalog No. ABIN6990596

Product Details anti-C1QTNF3 Antibody

Target: C1QTNF3 (C1q and Tumor Necrosis Factor Related Protein 3 (C1QTNF3))

Binding Specificity: AA 90-140

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QTNF3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Multiple isoforms of CTRP3 are known to exist. CTRP3 antibody is predicted to not recognize other members of the CTRP protein family.

Purification: CTRP3 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-CTRP3 antibody was raised against a peptide corresponding to 16 amino acids near the center of human CTRP3. The immunogen is located within amino acids 90-140 of CTRP3.

Isotype: IgG

Application Details

Application Notes: WB: 1 μ,g/mL, IHC: 2 μ,g/mL, IF: 10 μ,g/mL.

Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in mouse samples, Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CTRP3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CTRP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for C1QTNF3

Target: C1QTNF3 (C1q and Tumor Necrosis Factor Related Protein 3 (C1QTNF3))

Alternative Name: CTRP3 (C1QTNF3 Products)

Synonyms: Amacr antibody, zgc:110704 antibody, C1ATNF3 antibody, CORCS antibody, CORS antibody, CORS-26 antibody, CORS26 antibody, CTRP3 antibody, 2310005P21Rik antibody, Corcs antibody, Cors antibody, C1q and tumor necrosis factor related protein 3 antibody, alpha-methylacyl-CoA racemase antibody, C1q and TNF related 3 antibody, C1QTNF3 antibody, amacr antibody, C1qtnf3 antibody

Background: CTRP3 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. It has been suggested that CTRP3 may play a role in skeletal development.

Molecular Weight: Predicted: 27kD

Observed: 30 kD (Post-modyfication: 1 N-linked glycosylation) kDa

Gene ID: 114899

NCBI Accession: NP_852100

UniProt: Q9BXJ4