STK17A antibody (N-Term)

Catalog No. ABIN499768

This Rabbit Polyclonal antibody specifically detects STK17A in WB, IF and EIA. It exhibits reactivity toward Human.

Quick Overview for STK17A antibody (N-Term) (ABIN499768)

Target: STK17A (serine/threonine Kinase 17a (STK17A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK17A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-STK17A Antibody

Binding Specificity: N-Term

Specificity: DRAK1 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DRAK1. DRAK1 antibody has no cross responses to DRAK2, DAP or ZIP kinases.

Purification: Affinity chromatography purified via peptide column

Immunogen: Human DRAK1 (N-Terminus) Peptide

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: 0.5 - 1 μg/mL. A431 or MOLT4 whole cell lysate can be used as positivecontrol and an approximately 50 kDa band can be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for STK17A

Target: STK17A (serine/threonine Kinase 17a (STK17A))

Alternative Name: STK17A / DRAK1

Background: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases (1). DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues (1).Synonyms: DAP kinase-related apoptosis-inducing protein kinase 1, Serine/threonine-protein kinase 17A

Gene ID: 9263

UniProt: Q9UEE5