FEZ2 antibody (Center)

Catalog No. ABIN499834

This Rabbit Polyclonal antibody specifically detects FEZ2 in WB, IF and EIA. It exhibits reactivity toward Rat, Human and Mouse.

Quick Overview for FEZ2 antibody (Center) (ABIN499834)

Target: FEZ2 (Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2))

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEZ2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-FEZ2 Antibody

Binding Specificity: Center

Specificity: This antibody reacts to FEZ2.

Purification: Affinity chromatography purified via peptide column

Immunogen: FEZ2 antibody was raised against a 15 amino acid peptide from near the center of human FEZ2.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: 0.5 - 1 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for FEZ2

Target: FEZ2 (Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2))

Alternative Name: Zygin-2

Background: Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-z substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-z, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-z in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.Synonyms: FEZ2, Fasciculation and elongation protein zeta-2, Zygin II

Gene ID: 9637

NCBI Accession: NP_001036013

UniProt: Q9UHY8